Yan-Shen Shan Selected Research

Tyrosine Kinase Inhibitors

1/2019	Nuclear KIT induces a NFKBIB-RELA-KIT autoregulatory loop in imatinib-resistant gastrointestinal stromal tumors.
1/2013	Selecting tyrosine kinase inhibitors for gastrointestinal stromal tumor with secondary KIT activation-loop domain mutations.

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Yan-Shen Shan Research Topics

Disease

77	Neoplasms (Cancer) 04/2024 - 07/2005
35	Pancreatic Neoplasms (Pancreatic Cancer) 04/2024 - 10/2007
32	Adenocarcinoma 03/2024 - 08/2012
21	Stomach Neoplasms (Stomach Cancer) 01/2023 - 10/2011
15	Neoplasm Metastasis (Metastasis) 10/2023 - 04/2010
13	Carcinogenesis 01/2023 - 11/2014
7	Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor) 05/2019 - 08/2010
5	Hepatocellular Carcinoma (Hepatoma) 11/2022 - 05/2007
5	Disease Progression 01/2022 - 12/2011
5	Neuroendocrine Tumors (Neuroendocrine Tumor) 01/2021 - 07/2005
5	Carcinoma (Carcinomatosis) 12/2016 - 09/2005
4	Obesity 01/2023 - 05/2020
4	Primitive Neuroectodermal Tumors (PNET) 11/2022 - 11/2017
4	Biliary Tract Neoplasms (Biliary Tract Cancer) 10/2022 - 01/2016
4	Fibrosis (Cirrhosis) 01/2022 - 04/2013
3	Pancreatic Fistula (Pancreatic Fistulas) 06/2021 - 04/2013
3	Glioma (Gliomas) 04/2021 - 02/2013
3	Lymphatic Metastasis 01/2021 - 01/2007
2	Infarction (Infarctions) 11/2023 - 10/2022
2	COVID-19 09/2023 - 05/2022
2	Wounds and Injuries (Trauma) 01/2023 - 11/2022
2	Cholangiocarcinoma 10/2022 - 01/2020
2	Lung Neoplasms (Lung Cancer) 06/2022 - 06/2015
2	Colonic Neoplasms (Colon Cancer) 01/2022 - 12/2014
2	Cachexia 01/2022 - 12/2018
2	Head and Neck Neoplasms (Head and Neck Cancer) 08/2021 - 09/2005
2	Wound Infection (Wound Infections) 06/2021 - 07/2010
2	Microcephaly 05/2021 - 12/2019
2	Neutropenia 10/2020 - 02/2016
2	Pneumoperitoneum 03/2018 - 01/2015

Drug/Important Bio-Agent (IBA)

28	Gemcitabine FDA Link 03/2024 - 10/2007
17	Fluorouracil (Carac)FDA LinkGeneric 03/2024 - 10/2007
17	Proteins (Proteins, Gene)FDA Link 01/2024 - 08/2010
16	Leucovorin (Folinic Acid)FDA Link 03/2024 - 12/2011
15	Irinotecan (Camptosar)FDA LinkGeneric 03/2024 - 02/2016
6	Messenger RNA (mRNA)IBA 01/2024 - 11/2013
6	Small Interfering RNA (siRNA)IBA 01/2023 - 11/2014
6	EnzymesIBA 11/2022 - 09/2011
6	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2022 - 10/2007
6	OsteopontinIBA 03/2015 - 07/2010
5	Biomarkers (Surrogate Marker)IBA 01/2024 - 01/2017
5	Indicators and Reagents (Reagents)IBA 12/2023 - 08/2007
5	CytokinesIBA 06/2022 - 07/2010
5	Protein Isoforms (Isoforms)IBA 05/2021 - 07/2005
4	MicroRNAs (MicroRNA)IBA 01/2024 - 10/2015
4	AntigensIBA 01/2023 - 07/2018
4	CateninsIBA 02/2022 - 06/2014
4	Therapeutic UsesIBA 10/2021 - 10/2011
3	IntegrinsIBA 04/2024 - 10/2007
3	Glucose (Dextrose)FDA LinkGeneric 01/2023 - 01/2019
3	TensinsIBA 11/2022 - 03/2016
3	Phosphoric Monoester Hydrolases (Phosphatases)IBA 11/2022 - 03/2016
3	Cyclin D1IBA 02/2022 - 08/2010
3	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 10/2017
3	PlatinumIBA 07/2021 - 01/2016
3	Complementary DNA (cDNA)IBA 01/2020 - 01/2015
3	Interleukin-8 (Interleukin 8)IBA 01/2019 - 09/2016
3	Tumor Biomarkers (Tumor Markers)IBA 01/2019 - 04/2010
3	Everolimus FDA Link 11/2017 - 12/2016
2	130-nm albumin-bound paclitaxelIBA 03/2024 - 10/2023
2	Epithelial Cell Adhesion MoleculeIBA 12/2023 - 01/2020
2	GlycosaminoglycansIBA 12/2023 - 01/2020
2	CarbohydratesIBA 01/2023 - 01/2022
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 11/2022 - 10/2007
2	N-Methylaspartate (NMDA)IBA 10/2022 - 06/2015
2	Glycogen Synthase KinasesIBA 10/2022 - 03/2016
2	Matrix Metalloproteinases (MMPs)IBA 10/2022 - 01/2019
2	MethyltransferasesIBA 01/2022 - 10/2017
2	Interleukin-6 (Interleukin 6)IBA 01/2022 - 12/2014
2	RNA (Ribonucleic Acid)IBA 01/2022 - 01/2021
2	Monomeric GTP-Binding ProteinsIBA 01/2022 - 05/2017
2	Transforming Growth Factor beta (TGF-beta)IBA 04/2021 - 01/2020
2	Factor X (Stuart Factor)IBA 01/2021 - 08/2012
2	Vascular Endothelial Growth Factor CIBA 01/2021 - 01/2020
2	Histone Deacetylase InhibitorsIBA 01/2021 - 10/2011
2	Cisplatin (Platino)FDA LinkGeneric 10/2020 - 11/2014
2	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2020 - 08/2012
2	Codon (Codons)IBA 05/2019 - 01/2016
2	Protein-Arginine N-Methyltransferases (Methyltransferase, Protein Arginine)IBA 01/2019 - 12/2018
2	AgarIBA 01/2019 - 01/2018
2	Tyrosine Kinase InhibitorsIBA 01/2019 - 01/2013
2	Imatinib Mesylate (Gleevec)FDA Link 01/2019 - 01/2013
2	Carcinoembryonic AntigenIBA 01/2019 - 07/2018
2	Platelet-Derived Growth FactorIBA 01/2019 - 05/2015

Therapy/Procedure

24	Therapeutics 01/2023 - 01/2006
19	Drug Therapy (Chemotherapy) 01/2024 - 12/2002
8	Pancreaticoduodenectomy 01/2023 - 09/2005
5	Immunotherapy 10/2022 - 04/2019
4	Neoadjuvant Therapy 09/2023 - 09/2014
4	Length of Stay 11/2022 - 01/2006
3	Adjuvant Chemotherapy 09/2023 - 07/2021
3	Induction Chemotherapy 01/2022 - 12/2011
3	Lymph Node Excision (Lymph Node Dissection) 06/2019 - 01/2007
2	Radiotherapy 01/2023 - 10/2018
2	Gastrectomy 01/2023 - 11/2021
2	Artificial Respiration (Mechanical Ventilation) 11/2022 - 08/2016
2	Lasers (Laser) 10/2022 - 07/2010
2	Chemoradiotherapy 01/2022 - 12/2011
2	Adjuvant Chemoradiotherapy 01/2021 - 11/2015
2	Pancreatectomy 10/2020 - 04/2013